Abstract
The appropriateness of house dust mite specific immunotherapy in patients allergic to shrimps still remains unclear We present a clinical case as an immunological model for the strong sensitization to tropomyosin with symptoms of anaphylaxis due to shrimps and coexisting asthma due to house dust mite. The improvement in respiratory symptoms for house dust mite and in the food challenge for shrimps during mite immunotherapy with a known and high dosage of tropomyosin suggests the hypothesis that efficacy of mite immunotherapy in food allergy to tropomyosin may be dose dependent.
MeSH terms
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Administration, Sublingual
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Adolescent
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Animals
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Antigens, Dermatophagoides / immunology*
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Antigens, Dermatophagoides / metabolism
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Asthma / complications
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Asthma / drug therapy*
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Asthma / immunology
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Cross Reactions / physiology
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Desensitization, Immunologic*
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Food Hypersensitivity / complications
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Food Hypersensitivity / drug therapy*
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Food Hypersensitivity / immunology
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Humans
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Male
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Penaeidae / immunology
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Penaeidae / metabolism
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Pyroglyphidae / immunology
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Pyroglyphidae / metabolism
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Shellfish / adverse effects
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Treatment Outcome
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Tropomyosin / immunology*
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Tropomyosin / metabolism
Substances
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Antigens, Dermatophagoides
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Tropomyosin