De novo polycythaemia vera arising 5 years following acute myeloid leukemia remission: suggestion of a chemotherapy resistant JAK2 clone

Br J Haematol. 2012 Apr;157(2):266-7. doi: 10.1111/j.1365-2141.2011.08972.x. Epub 2011 Dec 8.
No abstract available

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Amino Acid Substitution
  • Antineoplastic Combined Chemotherapy Protocols / administration & dosage
  • Cytarabine / administration & dosage
  • Drug Resistance, Neoplasm / drug effects
  • Drug Resistance, Neoplasm / genetics*
  • Female
  • Humans
  • Janus Kinase 2 / genetics*
  • Leukemia, Myeloid, Acute / drug therapy*
  • Leukemia, Myeloid, Acute / enzymology
  • Leukemia, Myeloid, Acute / genetics*
  • Middle Aged
  • Mutation, Missense*
  • Polycythemia Vera / drug therapy
  • Polycythemia Vera / enzymology
  • Polycythemia Vera / genetics*

Substances

  • Cytarabine
  • JAK2 protein, human
  • Janus Kinase 2