Abstract
Between July 2011 and August 2011, the New Delhi metallo-beta-lactamase 1 (NDM-1) gene was detected in Klebsiella pneumoniae and Escherichia coli isolates obtained from six patients hospitalised in four healthcare facilities in northern Italy. The patient who had been hospitalised in New Delhi, India, from February to May 2011 and subsequently in the Bologna area, Italy, from May to July 2011, may have been the source of the outbreak. Our findings suggest ongoing spread of this carbapenem-resistance gene in Italy and highlight the need for intensive surveillance.
MeSH terms
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Carbapenems / pharmacology
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Disease Outbreaks*
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Drug Resistance, Bacterial
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Enterobacteriaceae Infections / microbiology
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Escherichia coli / drug effects
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Escherichia coli / genetics
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Escherichia coli / isolation & purification*
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Genes, Bacterial
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Hospitalization
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Humans
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India / ethnology
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Italy / epidemiology
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Klebsiella pneumoniae / drug effects
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Klebsiella pneumoniae / genetics
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Klebsiella pneumoniae / isolation & purification*
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Microbial Sensitivity Tests
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Retrospective Studies
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beta-Lactamases / genetics*
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beta-Lactamases / urine
Substances
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Carbapenems
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beta-Lactamases
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beta-lactamase NDM-1