[Intracerebral haemorrhage and postpartum cerebral angiopathy associated with the administration of sulprostone and norepinephrine]

Ann Fr Anesth Reanim. 2012 Jan;31(1):78-81. doi: 10.1016/j.annfar.2011.09.009. Epub 2011 Dec 6.
[Article in French]

Abstract

We report the case of a 29-year-old female who had developed a postpartum cerebral angiopathy (PCA) complicated by an intracerebral haematoma and convulsions, after a postpartum haemorrhage with sulprostone and norepinephrine infusion. PCA is an under diagnosed neurovascular pathology, responsible of reversible and non-specific symptoms. However, it can be complicated by haemorrhagic or ischemic stroke with vital or functional risks. As PCA is favored by vasoactive treatments, their administration in peripartum period, when it is imperative, should be strictly controlled.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Brain / diagnostic imaging
  • Cerebral Angiography
  • Cerebrovascular Disorders / chemically induced*
  • Dinoprostone / adverse effects
  • Dinoprostone / analogs & derivatives*
  • Female
  • Humans
  • Intracranial Hemorrhages / chemically induced*
  • Intracranial Pressure / physiology
  • Norepinephrine / adverse effects*
  • Postpartum Period*
  • Respiration, Artificial
  • Resuscitation
  • Seizures / chemically induced
  • Tomography, X-Ray Computed
  • Vasoconstrictor Agents / adverse effects*

Substances

  • Vasoconstrictor Agents
  • sulprostone
  • Dinoprostone
  • Norepinephrine