Cortical DC potentials were recorded while subjects were learning word pairs. The use of an elaborative mnemonic strategy resulted in a left frontal sustained negative shift. Its amplitude was independent of whether imagery mnemonics or semantic mnemonics were used. By contrast, posterior temporal potentials differed according to strategy: with imagery mnemonics, subjects had more symmetrical potentials over posterior temporal areas whereas with a semantic strategy, there was a left hemispheric preponderance of the DC potential. An interpretation within Stuss and Benson's theory on the frontal lobes is given.