Vancomycin-induced red man syndrome in pediatric oncology: still an issue?

Int J Clin Pharm. 2012 Feb;34(1):13-6. doi: 10.1007/s11096-011-9593-z. Epub 2011 Dec 13.

Abstract

Red man syndrome is a rare but possibly serious adverse reaction during treatment with intravenous vancomycin. It is extremely important that pediatricians, especially in oncology, recognize this reaction and treat it appropriately. Following two case-reports from a pediatric oncology setting, a series of practical recommendations to prevent or handle red man syndrome are described.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Anti-Bacterial Agents / administration & dosage
  • Anti-Bacterial Agents / adverse effects*
  • Child, Preschool
  • Drug Eruptions / diagnosis
  • Drug Eruptions / etiology*
  • Erythema / chemically induced*
  • Erythema / diagnosis
  • Humans
  • Infusions, Intravenous
  • Male
  • Pruritus / chemically induced
  • Pruritus / diagnosis
  • Syndrome
  • Vancomycin / administration & dosage
  • Vancomycin / adverse effects*

Substances

  • Anti-Bacterial Agents
  • Vancomycin