Abstract
In this communication, we demonstrate that graphene oxide (GO) greatly inhibits the peroxidatic activity of a horseradish peroxidase-mimicking DNAzyme. Combining this observation with the unique DNA/GO interactions, an ultrasensitive GO-based chemiluminescence DNA biosensing platform is developed.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Biomimetic Materials / metabolism
-
Biosensing Techniques / methods*
-
DNA / analysis*
-
DNA / chemistry
-
DNA, Catalytic / metabolism*
-
Graphite / chemistry*
-
HIV
-
Horseradish Peroxidase / metabolism*
-
Luminescent Measurements / methods*
-
Models, Molecular
-
Molecular Conformation
-
Oligonucleotide Probes / chemistry
-
Oxides / chemistry*
Substances
-
DNA, Catalytic
-
Oligonucleotide Probes
-
Oxides
-
Graphite
-
DNA
-
Horseradish Peroxidase