Abstract
We report on the first Neisseria gonorrhoeae isolate in the United States identified with high-level resistance to azithromycin. This report discusses the epidemiologic case investigation, the molecular studies of resistance-associated mutations and N. gonorrhoeae multiantigen sequence typing, and challenges posed by emerging gonococcal antimicrobial resistance.
Publication types
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Case Reports
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Adult
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Anti-Bacterial Agents / pharmacology*
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Azithromycin / pharmacology*
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Drug Resistance, Bacterial*
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Female
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Gonorrhea / microbiology*
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Hawaii
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Humans
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Male
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Microbial Sensitivity Tests
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Neisseria gonorrhoeae / drug effects*
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Neisseria gonorrhoeae / genetics
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Neisseria gonorrhoeae / immunology
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Young Adult
Substances
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Anti-Bacterial Agents
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Azithromycin