We studied 9145 workers allocated among Italian country employed in the same factory. Most of them were male, mean age 47,6 (20,2<x<71,9). Everybody was subjected to cardiovascular examination, electrocardiogram, blood chemistry: glycemia, total cholesterol, Hdl, Ldl, homocysteinemia, serum protein electrophoresis. BMI was lower in Lombardia than Center and South of the Country. Southern were older, we found important differences among people living in the different areas. Southern and people of the central lands had a higher cardiovascular risk than northern. Thirty workers (0.3%) had a risk about 20% (MCV V), one hundred about 15-20% (MCV IV). We think it's necessary to follow people after the study too, to make change their lifestyle and eating habits and to verify the effect on time.