Pain in patients with myotonic dystrophy type 2: a postal survey in Finland

Muscle Nerve. 2012 Jan;45(1):70-4. doi: 10.1002/mus.22249.

Abstract

Introduction: Widespread musculoskeletal pain is a well-known symptom of myotonic dystrophy type 2 (DM2), but so far it has been addressed in only a few studies.

Methods: A postal survey for all traceable DM2 patients (n = 132) was conducted. A specific questionnaire, and severity and interference subscales of the Brief Pain Inventory, quality of life (RAND-36), and modified Beck Depression Inventory were completed.

Results: The response rate was 70%. The mean age of respondents was 53 years, 59% of whom were women. Current pain was reported by 54%. Lifetime prevalence of pain was 76%. The mean intensity of pain at its highest in the last week was 5.9, and 2.3 at its lowest (on a numerical rating scale of 0-10). Quality of life was lower in DM2 patients who reported pain. In 18%, the depression score was noticeably different.

Conclusions: Pain of moderate severity and unpleasant muscular symptoms are common in DM2. DM2 should be taken into consideration in the differential diagnosis of musculoskeletal pain.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Depression / epidemiology
  • Depression / etiology
  • Female
  • Finland / epidemiology
  • Humans
  • Male
  • Middle Aged
  • Musculoskeletal Pain / complications*
  • Musculoskeletal Pain / epidemiology*
  • Myotonic Disorders / complications*
  • Myotonic Disorders / epidemiology*
  • Myotonic Dystrophy
  • Pain Measurement
  • Psychiatric Status Rating Scales
  • Quality of Life
  • Severity of Illness Index
  • Surveys and Questionnaires
  • Young Adult