Discovery of novel stem cell mobilizers that target the CXCR4 receptor

ChemMedChem. 2012 Feb 6;7(2):209-12. doi: 10.1002/cmdc.201100525. Epub 2011 Dec 20.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Benzylamines
  • Cyclams
  • Drug Evaluation, Preclinical
  • Hematopoietic Stem Cell Mobilization*
  • Hematopoietic Stem Cells / cytology
  • Heterocyclic Compounds / chemistry
  • Heterocyclic Compounds / pharmacology
  • Injections, Subcutaneous
  • Male
  • Mice
  • Mice, Inbred C57BL
  • Polyamines / chemistry
  • Pyrimidines / chemistry
  • Quinazolines / chemical synthesis
  • Quinazolines / chemistry
  • Quinazolines / pharmacology
  • Receptors, CXCR4 / antagonists & inhibitors*
  • Receptors, CXCR4 / metabolism
  • Regenerative Medicine

Substances

  • Benzylamines
  • Cyclams
  • Heterocyclic Compounds
  • Polyamines
  • Pyrimidines
  • Quinazolines
  • Receptors, CXCR4
  • pyrimidine
  • plerixafor