Learning to protect your genome on the fly

Mia T Levine; Harmit S Malik

doi:10.1016/j.cell.2011.12.001

Learning to protect your genome on the fly

Cell. 2011 Dec 23;147(7):1440-1. doi: 10.1016/j.cell.2011.12.001.

Authors

Mia T Levine¹, Harmit S Malik

Affiliation

¹ Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.

Abstract

Piwi-interacting RNAs (piRNAs) help defend host genomes against germline transposons. In this issue of Cell, Khurana et al. show how alterations in the piRNA-encoding loci within a single generation allow a naive fly genome to overcome the initially insurmountable challenge imposed by a newly encountered mobile element.

Publication types

Comment
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

Abstract

Publication types

Grants and funding