Abstract
In three patients with thioridazine toxicity, the electroretinogram (ERG) to red light was found to be below the average normal range. A significant increase in its amplitude appeared with cessation of therapy in two cases. A further deterioration of the ERG amplitude to all stimulus conditions (white, blue, and red lights) occurred when the dose of the medication was increased in the third patient.
Publication types
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Case Reports
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Clinical Trial
MeSH terms
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Adult
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Analysis of Variance
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Electroretinography / drug effects*
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Female
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Fluorescein Angiography
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Follow-Up Studies
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Fundus Oculi
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Humans
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Male
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Middle Aged
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Prospective Studies
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Retina / drug effects*
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Retina / physiopathology
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Schizophrenia / drug therapy
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Thioridazine / adverse effects*
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Vision Disorders / chemically induced*
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Vision Disorders / physiopathology