Metastases are the most common intraocular malignancy. Determination of the primary site and entire burden of disease as a part of initial staging is important in choosing the most appropriate management strategy. F-18 FDG PET/CT can demonstrate primary neoplasms and the whole-body total burden of disease. We present 2 cases of intraocular metastases from lung carcinoma where F-18 FDG PET/CT was useful as one-stop-shop imaging modality in detection of the primary and in assessment of total disease burden.