Pyrenocines J-M: four new pyrenocines from the endophytic fungus, Phomopsis sp

Fitoterapia. 2012 Apr;83(3):523-6. doi: 10.1016/j.fitote.2011.12.017. Epub 2011 Dec 30.

Abstract

Four new pyrenocines, named pyrenocines J-M (1-4), were isolated from an endophytic fungus, Phomopsis sp, by a bioassay-guided method. The structures of the new compound have been assigned from ¹H and ¹³C NMR spectra, DEPT, and by 2D COSY, HMQC, and HMBC experiments. Preliminary studied showed that compounds 1, 2 and 4 showed good antifungal, antibacterial, and algicidal properties, while compound 3 had good antibacterial and algicidal properties.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acrolein / analogs & derivatives
  • Acrolein / chemistry
  • Acrolein / isolation & purification
  • Acrolein / pharmacology*
  • Anti-Infective Agents / chemistry
  • Anti-Infective Agents / isolation & purification
  • Anti-Infective Agents / pharmacology*
  • Ascomycota / chemistry*
  • Biological Products / chemistry
  • Biological Products / pharmacology*
  • Endophytes / chemistry
  • Molecular Structure
  • Pyrones / chemistry
  • Pyrones / isolation & purification
  • Pyrones / pharmacology*

Substances

  • Anti-Infective Agents
  • Biological Products
  • Pyrones
  • Acrolein