An unusual caffeic acid derived bicyclic [2.2.2] octane lignan and other constituents from Cordia rufescens

Ademir E do Vale; Jorge M David; Edlene O dos Santos; Juceni P David; Lidercia C R C e Silva; Marcus V Bahia; Hugo N Brandão

doi:10.1016/j.phytochem.2011.09.019

An unusual caffeic acid derived bicyclic [2.2.2] octane lignan and other constituents from Cordia rufescens

Phytochemistry. 2012 Apr:76:158-61. doi: 10.1016/j.phytochem.2011.09.019. Epub 2012 Jan 14.

Authors

Ademir E do Vale¹, Jorge M David, Edlene O dos Santos, Juceni P David, Lidercia C R C e Silva, Marcus V Bahia, Hugo N Brandão

Affiliation

¹ Instituto de Química, Universidade Federal da Bahia, Salvador, BA, Brazil.

PMID: 22248687
DOI: 10.1016/j.phytochem.2011.09.019

Abstract

This work reports isolation of an unusual lignan with a bicyclic [2.2.2] octene skeleton, named rufescenolide (1), from stems of Cordia rufescens, along with β-sitosterol, stigmasterol, syringaldehyde, 3-β-O-D-glucopyranosyl-sitosterol, methyl caffeate, 4-methoxy-protocatechuic acid and methyl rosmarinate. Structural characterizations employed IR spectroscopic, ESIHRMS and mono and dimensional NMR spectroscopy.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Bridged Bicyclo Compounds / chemistry
Bridged Bicyclo Compounds / isolation & purification*
Caffeic Acids / chemistry*
Cordia / chemistry*
Hydroxybenzoates / chemistry
Lignans / chemistry*
Lignans / isolation & purification
Magnetic Resonance Spectroscopy
Molecular Structure
Octanes / chemistry*
Octanes / isolation & purification
Plant Stems / chemistry
Sitosterols / chemistry
Sitosterols / isolation & purification
Stigmasterol / chemistry
Stigmasterol / isolation & purification

Substances

Bridged Bicyclo Compounds
Caffeic Acids
Hydroxybenzoates
Lignans
Octanes
Sitosterols
rufescenolide
protocatechuic acid
gamma-sitosterol
Stigmasterol