Roux-en-Y choledochojejunostomy using novel magnetic compressive anastomats in canine model of obstructive jaundice

Hepatobiliary Pancreat Dis Int. 2012 Feb;11(1):81-8. doi: 10.1016/s1499-3872(11)60129-x.

Abstract

Background: The traditional hand-sewn Roux-en-Y choledochojejunostomy is technically complicated, and the incidence of postoperative complications has remained high. A set of novel magnetic compressive anastomats was introduced to facilitate choledochojejunostomy and improve the prognosis of patients.

Methods: After ligating the common bile duct for 7 days, 16 dogs were randomly divided into two groups (n=8 per group). Anastomats were used in the study group, and the traditional hand-sewn method was used in the control group for standard Roux-en-Y choledochojejunostomy. We compared the operation time, incidence of complications, gross appearance, and pathological disparity in stoma between the two groups in 1-month and 3-month follow-up examinations.

Results: The time spent on constructing the anastomosis for the study group was significantly shortened. Although no anastomotic stenosis occurred in the two groups, the narrowing rate of biliary-enteric anastomosis was much higher in the control group. There was one case of bile leakage in the control group, whereas no bile leakage occurred in the study group. A smoother surface, an improved layer apposition, and a lower local inflammatory response were identified in the anastomosis of the study group.

Conclusion: The structures of the novel magnetic compressive anastomats are simple, and they are time-saving, safe and efficient for performing Roux-en-Y choledochojejunostomy procedures in a canine model of obstructive jaundice.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anastomosis, Roux-en-Y / adverse effects
  • Anastomosis, Roux-en-Y / instrumentation*
  • Animals
  • Bilirubin / blood
  • Biomarkers / blood
  • Choledochostomy / adverse effects
  • Choledochostomy / instrumentation*
  • Disease Models, Animal
  • Dogs
  • Equipment Design
  • Jaundice, Obstructive / blood
  • Jaundice, Obstructive / surgery*
  • Magnetics / instrumentation*
  • Male
  • Surgical Equipment
  • Time Factors

Substances

  • Biomarkers
  • Bilirubin