Is there a role for free breathing non-contrast steady-state free precession renal MRA imaging for assessing live donors? A preliminary study

Br J Radiol. 2012 Aug;85(1016):e448-54. doi: 10.1259/bjr/16270927. Epub 2012 Jan 17.

Abstract

Objective: Accurate pre-operative evaluation of renal vascular anatomy is essential for successful renal harvest in live donor transplantation. Non-contrast renal MR angiographic (MRA) techniques are potentially well suited to the screening of donors; however, their restricted imaging field of view (FOV) has previously been an important limitation. We sought to assess whether the addition of a large FOV balanced fast field echo (BFFE) steady-state free precession (SSFP) sequence to non-contrast SSFP MRA could overcome this problem. Comparison with contrast-enhanced MRA (CE MRA) and findings at surgery were performed.

Methods: 22 potential renal donors each underwent SSFP and CE MRA. 11 out of 22 potential donors subsequently underwent a donor nephrectomy.

Results: All images were diagnostic. Both SSFP MRA and CE MRA identified an equal number of arteries. Surgery confirmed two accessory renal arteries, both demonstrated with both imaging techniques. A third accessory vessel was identified with both techniques on a kidney contralateral to the donated organ. 6 out of 11 procured kidneys demonstrated early branch arteries at surgery, 5 out of 6 of which had been depicted on both SSFP and CE MRA. The median grading of image quality for main renal arteries was slightly better for CE MRA (p=0.048), but for accessory vessels it was better for SSFP MRA.

Conclusion: This pilot study indicates that by combining free-breathing SSFP MRA with large-FOV bFFE images, an accurate depiction of renal vascular anatomy without the need for intravenous contrast administration can be obtained, as compared with surgical findings and CE MRA.

Publication types

  • Evaluation Study

MeSH terms

  • Adult
  • Collateral Circulation / physiology
  • Contrast Media
  • Female
  • Humans
  • Kidney / blood supply*
  • Kidney Transplantation / methods*
  • Living Donors*
  • Magnetic Resonance Angiography / methods*
  • Male
  • Middle Aged
  • Nephrectomy
  • Pilot Projects
  • Preoperative Care / methods
  • Prospective Studies
  • Renal Artery / abnormalities*
  • Respiration

Substances

  • Contrast Media