On the parallel deterioration of lexico-semantic processes in the bilinguals' two languages: evidence from Alzheimer's disease

Neuropsychologia. 2012 Apr;50(5):740-53. doi: 10.1016/j.neuropsychologia.2012.01.008. Epub 2012 Jan 13.

Abstract

In this article we aimed to assess how Alzheimer's disease (AD), which is neurodegenerative, affects the linguistic performance of early, high-proficient bilinguals in their two languages. To this end, we compared the Picture Naming and Word Translation performances of two groups of AD patients varying in disease progression (Mild and Moderate) with that of bilingual individuals diagnosed with mild cognitive impairment (MCI). The results revealed that the linguistic deterioration caused by AD affected the two languages similarly. We also found that cognate status and word frequency were two major determinants of language performance in all three groups of participants. These results are consistent with the notion of a common neural substrate recruited to represent and process the two languages of high-proficient bilinguals.

Publication types

  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Alzheimer Disease / complications*
  • Analysis of Variance
  • Cognitive Dysfunction / complications*
  • Female
  • Humans
  • Language Disorders / diagnosis
  • Language Disorders / etiology*
  • Male
  • Mental Status Schedule
  • Multilingualism*
  • Names
  • Neuropsychological Tests
  • Paired-Associate Learning
  • Photic Stimulation
  • Regression Analysis
  • Semantics*
  • Surveys and Questionnaires
  • Translating
  • Vocabulary