Stratifying the risk of venous thromboembolism in otolaryngology

Otolaryngol Head Neck Surg. 2012 May;146(5):719-24. doi: 10.1177/0194599811434383. Epub 2012 Jan 18.

Abstract

Objective: The consequences of perioperative venous thromboembolism (VTE) are devastating; identifying patients at risk is an essential step in reducing morbidity and mortality. The utility of perioperative VTE risk assessment in otolaryngology is unknown. This study was designed to risk-stratify a diverse population of otolaryngology patients for VTE events.

Study design: Retrospective cohort study.

Setting: Single-institution academic tertiary care medical center.

Subjects and methods: Adult patients presenting for otolaryngologic surgery requiring hospital admission from 2003 to 2010 who did not receive VTE chemoprophylaxis were included. The Caprini risk assessment was retrospectively scored via a validated method of electronic chart abstraction. Primary study variables were Caprini risk scores and the incidence of perioperative venous thromboembolic outcomes.

Results: A total of 2016 patients were identified. The overall 30-day rate of VTE was 1.3%. The incidence of VTE in patients with a Caprini risk score of 6 or less was 0.5%. For patients with scores of 7 or 8, the incidence was 2.4%. Patients with a Caprini risk score greater than 8 had an 18.3% incidence of VTE and were significantly more likely to develop a VTE when compared to patients with a Caprini risk score less than 8 (P < .001). The mean risk score for patients with VTE (7.4) was significantly higher than the risk score for patients without VTE (4.8) (P < .001).

Conclusion: The Caprini risk assessment model effectively risk-stratifies otolaryngology patients for 30-day VTE events and allows otolaryngologists to identify patient subgroups who have a higher risk of VTE in the absence of chemoprophylaxis.

MeSH terms

  • Adult
  • Chi-Square Distribution
  • Female
  • Humans
  • Incidence
  • Male
  • Otorhinolaryngologic Surgical Procedures*
  • Postoperative Complications / epidemiology
  • Postoperative Complications / etiology*
  • Postoperative Complications / prevention & control*
  • Retrospective Studies
  • Risk Assessment / methods*
  • Risk Factors
  • Statistics, Nonparametric
  • Venous Thromboembolism / epidemiology
  • Venous Thromboembolism / etiology*
  • Venous Thromboembolism / prevention & control*