Specific p53 mutations do not impact results of alemtuzumab therapy among patients with chronic lymphocytic leukemia

Leuk Lymphoma. 2012 Sep;53(9):1817-9. doi: 10.3109/10428194.2012.658794. Epub 2012 Mar 1.
No abstract available

Publication types

  • Letter

MeSH terms

  • Adult
  • Aged
  • Alemtuzumab
  • Antibodies, Monoclonal, Humanized / administration & dosage
  • Antibodies, Monoclonal, Humanized / therapeutic use*
  • Antineoplastic Agents / administration & dosage
  • Antineoplastic Agents / therapeutic use
  • Chromosome Deletion
  • Chromosomes, Human, Pair 17 / genetics
  • Dose-Response Relationship, Drug
  • Drug Administration Schedule
  • Female
  • Humans
  • Kaplan-Meier Estimate
  • Leukemia, Lymphocytic, Chronic, B-Cell / drug therapy*
  • Leukemia, Lymphocytic, Chronic, B-Cell / genetics*
  • Male
  • Middle Aged
  • Mutation*
  • Retrospective Studies
  • Treatment Outcome
  • Tumor Suppressor Protein p53 / genetics*

Substances

  • Antibodies, Monoclonal, Humanized
  • Antineoplastic Agents
  • Tumor Suppressor Protein p53
  • Alemtuzumab