We investigate via experiments and simulations the statistical properties and the accumulation of nonlinear transmission impairments in coherent systems without optical dispersion compensation. We experimentally show that signal distortion due to Kerr nonlinearity can be modeled as additive Gaussian noise, and we demonstrate that its variance has a supra-linear dependence on propagation distance for 100 Gb/s transmissions over both low dispersion and standard single mode fiber. We propose a simple empirical model to account for linear and nonlinear noise accumulation, and to predict system performance for a wide range of distances, signal powers and optical noise levels.