Galactomannan testing might be useful for early diagnosis of fusariosis

Małgorzata Mikulska; Elisa Furfaro; Valerio Del Bono; Francesca Gualandi; Anna Maria Raiola; Maria Pia Molinari; Paola Gritti; Maurizio Sanguinetti; Brunella Posteraro; Andrea Bacigalupo; Claudio Viscoli

doi:10.1016/j.diagmicrobio.2011.12.009

Galactomannan testing might be useful for early diagnosis of fusariosis

Diagn Microbiol Infect Dis. 2012 Apr;72(4):367-9. doi: 10.1016/j.diagmicrobio.2011.12.009. Epub 2012 Jan 26.

Authors

Małgorzata Mikulska¹, Elisa Furfaro, Valerio Del Bono, Francesca Gualandi, Anna Maria Raiola, Maria Pia Molinari, Paola Gritti, Maurizio Sanguinetti, Brunella Posteraro, Andrea Bacigalupo, Claudio Viscoli

Affiliation

¹ Division of Infectious Diseases, San Martino University Hospital, 16132 Genoa, Italy. [email protected]

PMID: 22280997
DOI: 10.1016/j.diagmicrobio.2011.12.009

Abstract

Galactomannan (GM) is used to diagnose aspergillosis. We present a case of a hematopoietic stem cell transplantation recipient with fusariosis who received early antifungal treatment based on GM positivity. Additionally, 3 Fusarium isolates tested positive for GM. Fusarium is another mold containing GM. GM might be useful for diagnosing fusariosis in high-risk patients.

Publication types

Case Reports

MeSH terms

Antifungal Agents / therapeutic use*
Early Diagnosis
Fatal Outcome
Female
Fusariosis / diagnosis*
Fusariosis / drug therapy
Fusariosis / microbiology
Fusarium / classification
Fusarium / drug effects
Fusarium / genetics
Fusarium / isolation & purification*
Galactose / analogs & derivatives
Hematopoietic Stem Cell Transplantation / adverse effects*
Humans
Mannans / blood*
Middle Aged
beta-Glucans / blood

Substances

Antifungal Agents
Mannans
beta-Glucans
galactomannan
Galactose