Abstract
A transcription regulation system initiated by DNA nanostructure changes was designed and constructed. Using the toehold system, specific DNA strands induced the opening of the tubular structure. A transcription product from the purified tube-attached dsDNA template was observed by addition of DNA strands that were specific for opening the tubular structure.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Base Sequence
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Biotin / chemistry
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DNA / chemistry*
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DNA-Directed RNA Polymerases / chemistry
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Disulfides
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Gene Expression Regulation
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Imaging, Three-Dimensional
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Molecular Sequence Data
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Nanocomposites
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Nanotechnology / methods*
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Nucleic Acid Conformation
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Stress, Mechanical
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Transcription, Genetic
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Viral Proteins / chemistry
Substances
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Disulfides
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Viral Proteins
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Biotin
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DNA
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bacteriophage T7 RNA polymerase
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DNA-Directed RNA Polymerases