Recurrence after successful treatment among patients with multidrug-resistant tuberculosis

Int J Tuberc Lung Dis. 2011 Oct;15(10):1331-3. doi: 10.5588/ijtld.11.0098.

Abstract

A retrospective review was conducted of patients with multidrug-resistant tuberculosis (MDR-TB) to elucidate the rate of recurrence after successful treatment. Of 123 MDR-TB patients, 90 were declared as 'cured' or 'treatment completed' after individualised treatment; four (4.4%) experienced recurrence. All patients with recur- rent MDR-TB were documented as 'treatment completed' after treatment. Recurrence of MDR-TB is possible after successful treatment, particularly among those documented as 'treatment completed'.

MeSH terms

  • Adult
  • Aged
  • Antitubercular Agents / therapeutic use*
  • Chi-Square Distribution
  • Drug Resistance, Multiple, Bacterial*
  • Female
  • Humans
  • Kaplan-Meier Estimate
  • Male
  • Microbial Sensitivity Tests
  • Middle Aged
  • Mycobacterium tuberculosis / drug effects*
  • Mycobacterium tuberculosis / isolation & purification
  • Recurrence
  • Republic of Korea
  • Retrospective Studies
  • Sputum / microbiology
  • Time Factors
  • Treatment Outcome
  • Tuberculosis, Multidrug-Resistant / diagnosis
  • Tuberculosis, Multidrug-Resistant / drug therapy*
  • Tuberculosis, Multidrug-Resistant / microbiology
  • Tuberculosis, Pulmonary / diagnosis
  • Tuberculosis, Pulmonary / drug therapy*
  • Tuberculosis, Pulmonary / microbiology

Substances

  • Antitubercular Agents