DNA pillars constructed from an i-motif stem and duplex branches

Yang Yang; Chao Zhou; Tao Zhang; Enjun Cheng; Zhongqiang Yang; Dongsheng Liu

doi:10.1002/smll.201102061

DNA pillars constructed from an i-motif stem and duplex branches

Small. 2012 Feb 20;8(4):552-6. doi: 10.1002/smll.201102061. Epub 2012 Jan 30.

Authors

Yang Yang¹, Chao Zhou, Tao Zhang, Enjun Cheng, Zhongqiang Yang, Dongsheng Liu

Affiliation

¹ National Center for Nanoscience and Technology, Beijing 100190, China.

PMID: 22287104
DOI: 10.1002/smll.201102061

Abstract

At an acidic pH, cytosine-rich DNA strands can form i-motif tetramers. Pillar-like DNA structures are self-assembled with such i-motifs as the central stems. The central stem has some overhanging structures that can enable hybridization with complementary units by Watson-Crick pairing and, thus, multiple i-motifs can join to form the pillar.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Base Sequence
Circular Dichroism
DNA / chemistry*
DNA / ultrastructure
Electrophoresis, Polyacrylamide Gel
Gold
Hydrogen-Ion Concentration
Metal Nanoparticles / ultrastructure
Models, Molecular
Nucleotide Motifs*

Substances

Gold
DNA