Abstract
During a β-lactam resistance surveillance study, 12 IMP-18-positive Pseudomonas aeruginosa isolates belonging to 9 different pulsed-field gel electrophoresis groups were identified. In nine isolates, a class I integron with a novel gene array was identified that contained bla(IMP-18) and bla(OXA-224), while in two isolates the class I integron contained bla(IMP-18) and bla(OXA-2) but in a new arrangement. Our findings show the dissemination of two novel class I integrons in P. aeruginosa from different regions of Puerto Rico.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Aged
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Aged, 80 and over
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Electrophoresis, Gel, Pulsed-Field
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Female
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Humans
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Infant
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Integrons / genetics*
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Male
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Microarray Analysis
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Microbial Sensitivity Tests
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Middle Aged
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Molecular Sequence Data
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Polymerase Chain Reaction
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Pseudomonas Infections / microbiology*
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Pseudomonas aeruginosa / drug effects
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Pseudomonas aeruginosa / genetics*
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Puerto Rico
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beta-Lactamases / genetics*
Substances
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beta-lactamase OXA-2
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beta-lactamase OXA-4
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beta-Lactamases
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beta-lactamase IMP-18, Pseudomonas aeruginosa