LINAC based radiosurgery and radiotherapy for neurosurgical diseases: what have we learnt so far

Med J Malaysia. 2011 Oct;66(4):346-9.

Abstract

Background: Stereotactic radiosurgery uses a single fraction high dose radiation while stereotactic radiotherapy uses multifractionated lower dose focused radiation.

Materials and methods: Radiosurgery used rigid CRW head frame while stereotactic radiotherapy utilized GTC or HNL relocatable frames. Stereotactic planning and radiation involved Radionics X-plan and LINAC system.

Results: Since December 2001, we have treated 83 lesions from 77 patients using either radiosurgery or fractionated stereotactic radiotherapy. Eighty six percent (86%) of our treated lesions showed favourable outcomes with median follow-up of 32 months (0-7 years).

Conclusions: Our lessons from LINAC precision radiation therapy uphold its value as a promising and effective tool in treating a range of nervous system pathologies.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Brain Neoplasms / radiotherapy*
  • Brain Neoplasms / surgery*
  • Child
  • Dose Fractionation, Radiation*
  • Female
  • Humans
  • Intracranial Arteriovenous Malformations / radiotherapy*
  • Intracranial Arteriovenous Malformations / surgery*
  • Male
  • Middle Aged
  • Radiosurgery*