Abstract
Two new spirostanols and a new furostanol, reinocarnoside A (1), B (2) and C (3), were isolated from the roots of Reineckia carnea, together with two known compounds, (25S)-1β,3β,4β-trihydroxyspirostan-5β-yl-O-β-D-glucopyranoside (4), kitigenin-5β-O-β-D-glucopyranoside (5). The structures of three new compounds were elucidated by spectroscopic methods including 1-D NMR, 2-D NMR and MS spectrums, and their anticancer activities were evaluated by MTT method.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antineoplastic Agents / pharmacology*
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Glycosides / analysis*
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Glycosides / isolation & purification
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Glycosides / pharmacology
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Hep G2 Cells / drug effects
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Humans
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Liliaceae / chemistry*
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MCF-7 Cells / drug effects
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Magnetic Resonance Spectroscopy
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Mass Spectrometry
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Molecular Structure
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Plant Extracts / analysis*
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Plant Extracts / isolation & purification
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Plant Extracts / pharmacology
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Plant Roots / chemistry*
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Spirostans / analysis*
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Spirostans / isolation & purification
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Spirostans / pharmacology
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Sterols / analysis*
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Sterols / isolation & purification
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Sterols / pharmacology
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Tetrazolium Salts
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Thiazoles
Substances
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Antineoplastic Agents
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Glycosides
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Plant Extracts
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Spirostans
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Sterols
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Tetrazolium Salts
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Thiazoles
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furostanol glycoside
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thiazolyl blue