Assessment of risk factors for in-hospital mortality after intensive care unit discharge

Biomarkers. 2012 Mar;17(2):180-5. doi: 10.3109/1354750X.2012.654407. Epub 2012 Feb 11.

Abstract

Context: Post-intensive care unit (ICU) mortality predictors are unknown.

Objective: To assess post-ICU in-hospital mortality predictors.

Materials and methods: Analysis of 296 patients discharged alive from a medical-surgical ICU during an 18-month period.

Results: Post-ICU in-hospital mortality was 22.6%. Nonsurvivors had significantly higher Charlson comorbidity score and more often had a tracheostomy. C-reactive protein (CRP) "alert measurement", ≥ 6 mg/dL, independently discriminated survivors from nonsurvivors.

Discussion: A CRP "alert measurement" or the need for tracheostomy may be used to identify patients with high risk of dying after ICU discharge.

Conclusions: Charlson comorbidity score, CRP and tracheostomy predicted post-ICU in-hospital mortality.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • C-Reactive Protein / analysis*
  • Female
  • Hospital Mortality*
  • Humans
  • Intensive Care Units*
  • Male
  • Middle Aged
  • Patient Discharge
  • Portugal
  • Retrospective Studies
  • Risk Assessment
  • Risk Factors
  • Survival Analysis
  • Tracheostomy / mortality

Substances

  • C-Reactive Protein