[Morphologic and morphometric analysis of atheromatous changes in the aorta in silibinin-treated cholesterin-fed rabbits]

Morphol Igazsagugyi Orv Sz. 1990 Jul;30(3):202-7.
[Article in Hungarian]

Abstract

Authors studied the effect of Silibinin of antioxidative effect on cholesterin sclerosis of rabbits. Qualitative analysis of aorta sections, macroscopic and microscopic morphometric examination of aorta were the applied methods. Their results seem to show that Silibinin has a favourable influence on cholesterin sclerosis. According to their opinion only joint use of qualitative and quantitative macroscopic and microscopic methods can provide basis for really accurate judgment of any atheromatose change.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Aorta / drug effects
  • Aorta / pathology*
  • Aortic Diseases / chemically induced*
  • Aortic Diseases / drug therapy
  • Aortic Diseases / pathology
  • Arteriosclerosis / chemically induced
  • Arteriosclerosis / diagnosis
  • Arteriosclerosis / drug therapy*
  • Cholesterol, Dietary / administration & dosage
  • Cholesterol, Dietary / adverse effects*
  • Rabbits
  • Silymarin / administration & dosage
  • Silymarin / pharmacology*

Substances

  • Cholesterol, Dietary
  • Silymarin