Sequence typing confirms that a predominant Listeria monocytogenes clone caused human listeriosis cases and outbreaks in Canada from 1988 to 2010

J Clin Microbiol. 2012 May;50(5):1748-51. doi: 10.1128/JCM.06185-11. Epub 2012 Feb 15.

Abstract

Human listeriosis outbreaks in Canada have been predominantly caused by serotype 1/2a isolates with highly similar pulsed-field gel electrophoresis (PFGE) patterns. Multilocus sequence typing (MLST) and multi-virulence-locus sequence typing (MVLST) each identified a diverse population of Listeria monocytogenes isolates, and within that, both methods had congruent subtypes that substantiated a predominant clone (clonal complex 8; virulence type 59; proposed epidemic clone 5 [ECV]) that has been causing human illness across Canada for more than 2 decades.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Canada / epidemiology
  • Cluster Analysis
  • DNA, Bacterial / chemistry
  • DNA, Bacterial / genetics
  • Disease Outbreaks*
  • Humans
  • Listeria monocytogenes / classification*
  • Listeria monocytogenes / genetics*
  • Listeria monocytogenes / isolation & purification
  • Listeriosis / epidemiology*
  • Listeriosis / microbiology*
  • Molecular Epidemiology
  • Molecular Sequence Data
  • Molecular Typing*
  • Sequence Analysis, DNA

Substances

  • DNA, Bacterial

Associated data

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