AchR-positive myasthenia gravis with MRI evidence of early muscle atrophy

J Clin Neurosci. 2012 Jun;19(6):918-9. doi: 10.1016/j.jocn.2011.09.022. Epub 2012 Feb 15.

Abstract

Muscle atrophy, when it occurs in myasthenia gravis (MG), is usually associated with long-standing disease or with chronic corticosteroid treatment. Early muscle atrophy in a steroid-naive patient has been reported previously only in muscle-specific tyrosine kinase (MuSK)-MG. We report a 63-year-old male patient with acetylcholine receptor (AchR)-positive MG with a short duration of disease, no steroid treatment and MRI evidence of muscle atrophy.

Publication types

  • Case Reports

MeSH terms

  • Autoantibodies / metabolism*
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Muscular Atrophy / diagnosis*
  • Muscular Atrophy / etiology
  • Myasthenia Gravis / complications
  • Myasthenia Gravis / diagnosis*
  • Receptors, Cholinergic / immunology*

Substances

  • Autoantibodies
  • Receptors, Cholinergic