[Naloxone-induced pulmonary edema. Case report with review of the literature and critical evaluation]

Anaesthesist. 2012 Feb;61(2):129-36. doi: 10.1007/s00101-012-1982-8. Epub 2012 Feb 23.
[Article in German]

Abstract

A case of pulmonary edema after the administration of naloxone for laparoscopic splenectomy is reported. Previous reports of naloxone-induced pulmonary edema are listed and reviewed. The clinical course is compared to other forms of non-cardiogenic pulmonary edema. Uncertainty remains about the underlying pathophysiological process and the true impact of naloxone on the development of pulmonary edema.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Airway Obstruction / etiology
  • Airway Obstruction / therapy
  • Analgesics, Opioid / adverse effects
  • Analgesics, Opioid / antagonists & inhibitors
  • Drug Overdose
  • Echocardiography
  • Fluid Therapy
  • Humans
  • Laparoscopy
  • Male
  • Naloxone / adverse effects*
  • Narcotic Antagonists / adverse effects*
  • Oxygen / blood
  • Platelet Count
  • Positive-Pressure Respiration
  • Pulmonary Edema / chemically induced*
  • Pulmonary Edema / diagnostic imaging
  • Pulmonary Edema / therapy
  • Purpura, Thrombocytopenic, Idiopathic / surgery
  • Radiography
  • Respiration, Artificial
  • Respiratory Function Tests
  • Splenectomy

Substances

  • Analgesics, Opioid
  • Narcotic Antagonists
  • Naloxone
  • Oxygen