Abstract
There is increased serum CRH with decreased lesional skin CRHR-1 gene expression in psoriasis and atopic dermatitis, suggesting possible involvement in stress-induced worsening of symptoms.
Publication types
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Letter
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Research Support, N.I.H., Extramural
MeSH terms
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Adult
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Aged
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Corticotropin-Releasing Hormone / blood*
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Dermatitis, Atopic / genetics
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Dermatitis, Atopic / immunology*
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Disease Progression
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Female
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Gene Expression Regulation*
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Genetic Association Studies
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Humans
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Inflammation Mediators / metabolism
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Interleukin-8 / blood
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Male
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Mast Cells / immunology
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Mast Cells / pathology
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Middle Aged
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Psoriasis / genetics
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Psoriasis / immunology*
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Receptors, Corticotropin-Releasing Hormone / genetics*
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Skin / pathology
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Vascular Endothelial Growth Factor A / genetics
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Vascular Endothelial Growth Factor A / metabolism
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Young Adult
Substances
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Inflammation Mediators
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Interleukin-8
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Receptors, Corticotropin-Releasing Hormone
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Vascular Endothelial Growth Factor A
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CRF receptor type 1
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Corticotropin-Releasing Hormone