[Distal and late ureteral obstruction: a rare complication following dextranomer/hyaluronic acid injection for vesicoureteral reflux in children]

Prog Urol. 2012 Mar;22(3):192-4. doi: 10.1016/j.purol.2011.10.003. Epub 2011 Nov 29.
[Article in French]

Abstract

Surgically relevant obstruction after dextranomer/hyaluronic acid injection (Dx/Ha, Deflux(®)) for the treatment of vesicoureteral reflux (VUR) is rare with a 0.6% incidence. It occurs usually during the early postoperative period. We report here the case of a 9-year-old boy with a history of VUR who was previously treated with Deflux(®) and was referred more than 2 years later with acute flank pain (as he already did 2 weeks after surgery with a spontaneous relief under medical treatment). Initial radiological investigations showed hydronephrosis caused by distal ureteral obstruction which required open surgery removal of the Dx/Ha and Cohen procedure. This is the second case of delayed symptomatic obstruction due to Dx/Ha reported in the literature.

MeSH terms

  • Child
  • Dextrans / administration & dosage
  • Dextrans / adverse effects*
  • Humans
  • Hyaluronic Acid / administration & dosage
  • Hyaluronic Acid / adverse effects*
  • Injections, Intralesional
  • Male
  • Time Factors
  • Ureteral Obstruction / chemically induced*
  • Ureteral Obstruction / pathology
  • Vesico-Ureteral Reflux / therapy*

Substances

  • Dextrans
  • dextranomer-hyaluronic acid copolymer
  • Hyaluronic Acid