Clinico-pathological correlates of incidentally revealed thyroid swelling in Bihar, India

J Pharm Bioallied Sci. 2012 Jan;4(1):51-5. doi: 10.4103/0975-7406.92730.

Abstract

Background: Global prevalence of thyroid cancer has been on the rise in recent decades.

Objectives: To study the clinical presentations to reach an agreement for diagnosis and optimal management of incidentally revealed thyroid swellings for early diagnosis.

Materials and methods: A prospective study was carried out on 178 cases of incidentally detected thyroid swelling attending a tertiary care teaching institute of Kishanganj Bihar. All the cases were subjected to a thorough clinical examination followed by evidence-based interventions. Fine needle aspiration cytology was done in all the cases preoperatively as out-patients basis and histopathologically confirmed postoperatively.

Results: The highest incidence of thyroid swelling (75.84%) was found in the age group of 20-40 years; a female preponderance was noted in the ratio 4:1. The duration of swelling ranged from six months to three years. Difficulty in swallowing and breathing was complained by 23 (12.9%) and 18 (10.1%) of the patients respectively. Typically the swellings were located in the right lobe. Commonly the subjects in our study were in euthyroid state (90%) and were with firm swellings (66.7%). Follicular and anaplastic carcinoma was important postoperative cytological findings. Majority of surgical intervention was hemithyroidectomy (55.06%).

Conclusion: Incidentally revealed thyroid swelling was quite high in eastern India for which we need a consensus line of intervention.

Keywords: Bihar; fine needle aspiration cytology; thyroid swelling.