Moving molecular targeted drug therapy towards personalized medicine: issues related to clinical trial design

Mol Oncol. 2012 Apr;6(2):196-203. doi: 10.1016/j.molonc.2012.01.009. Epub 2012 Feb 16.

Abstract

With the event of new Molecular targets, clinical trial design requirements to perform these trials are changing. This paper discusses some of the considerations that need to be taken into account when designing a trial, including those trials that assess combinations of targets.

Publication types

  • Review

MeSH terms

  • Antineoplastic Agents / therapeutic use*
  • Clinical Trials as Topic*
  • Humans
  • Neoplasms / drug therapy*
  • Precision Medicine*
  • Research Design

Substances

  • Antineoplastic Agents