Staple-line reinforcement with a thrombin matrix during laparoscopic sleeve gastrectomy for morbid obesity: a case series

J Laparoendosc Adv Surg Tech A. 2012 Apr;22(3):249-53. doi: 10.1089/lap.2011.0372. Epub 2012 Mar 6.

Abstract

Background: Laparoscopic sleeve gastrectomy (LSG) represents a valid option for morbidly obese patients, either as a primary or as a staged procedure. Staple-line reinforcement (SLR) is strongly advocated to decrease the chance of bleeding. The aim of this article is to report our experience with a new technique of SLR using a thrombin-gelatin matrix in a series of morbidly obese patients subjected to LSG.

Subjects and methods: Patients subjected to LSG using a thrombin-gelatin matrix for SLR from April 2010 to April 2011 were included in the study. Each patient's record was registered and prospectively collected for the analysis.

Results: Seventy-four patients were subjected to LSG using a thrombin matrix for SLR. There were 56 female and 18 male subjects with a mean age of 44.8 years (range, 16-64 years). Mean preoperative body mass index was 46.2 kg/m(2) (range, 40-72 kg/m(2)). Mean operative time was 74.4 minutes (range, 58-96 minutes). Mean time for application of the thrombin matrix was 4.8 minutes (range, 3.2-6.6 minutes). Mean postoperative hospital stay was 3.4 days (range, 2-62 days). Mean follow-up was 8.2 months (range, 3-12 months). Mean postoperative body mass index was 36.2 kg/m(2) (range, 30-42 kg/m(2)), and mean percentage excess weight loss was 34.2% (range, 28.4%-42.8%). We observed two major postoperative complications (2.7%): One gastric stump leak (1.3%) and one major bleeding from the trocar site (1.3%), both successfully treated by laparoscopic re-exploration.

Conclusion: LSG with a thrombin matrix for SLR is a safe operation and a valid alternative to other well-established techniques.

MeSH terms

  • Adolescent
  • Adult
  • Body Mass Index
  • Female
  • Gastrectomy / methods*
  • Gelatin Sponge, Absorbable / therapeutic use*
  • Hemostasis, Surgical / methods*
  • Humans
  • Laparoscopy / methods*
  • Middle Aged
  • Obesity, Morbid / surgery*
  • Postoperative Complications / prevention & control
  • Surgical Stapling / methods*
  • Time Factors
  • Treatment Outcome

Substances

  • FloSeal Matrix