Utilization of available prenatal screening and diagnosis: effects of the California screen program

J Perinatol. 2012 Dec;32(12):907-12. doi: 10.1038/jp.2012.8. Epub 2012 Mar 8.

Abstract

Objective: In 2009, the California Genetic Disease Branch introduced an aneuploidy screening program allowing Medi-Cal (state insured) patients access to state-sponsored first-trimester screening. The objective of this study was to assess the effect of greater access to prenatal screening on available resources at a single center.

Study design: Data of prenatal screening and diagnostic procedures performed 4 months before the introduction of the program were compared with those of 12 months following the introduction.

Result: Between December 2008 and March 2010, 7689 women underwent first trimester screening, 1286 underwent amniocentesis and 398 underwent chorionic villus sampling. When a comparison was made between the 4 months before and the 12 months after the program's introduction, a greater number of nuchal translucency (NT) examinations was seen to have been performed (384 per month vs 513 per month, P=0.001). Prenatal diagnostic procedures did not increase, but a greater proportion was performed for positive screen results.

Conclusion: Introduction of the California screening program was associated with increased NT procedures and fewer invasive procedures for advanced maternal age.

Publication types

  • Comparative Study

MeSH terms

  • Academic Medical Centers
  • Adult
  • Amniocentesis / methods*
  • Amniocentesis / statistics & numerical data
  • California
  • Chorionic Villi Sampling / methods
  • Chorionic Villi Sampling / statistics & numerical data*
  • Female
  • Health Services Accessibility / organization & administration*
  • Humans
  • Incidence
  • Infant, Newborn
  • Middle Aged
  • Nuchal Translucency Measurement / methods
  • Nuchal Translucency Measurement / statistics & numerical data*
  • Pregnancy
  • Pregnancy Trimester, First
  • Prenatal Diagnosis / methods
  • Prenatal Diagnosis / statistics & numerical data*
  • Program Evaluation
  • Quality Improvement
  • Risk Assessment