Abstract
The methanol extract of an assemblage of Halimeda stuposa and a Dictyota sp., yielded three natural products characteristic of Dictyota sp., and one of Halimeda sp. These included the xenicane diterpene 4-hydroxydictyolactone (1), and the diterpenes dictyol E (2), 8a,11-dihydroxypachydictyol A (3) and indole-3-carboxaldehyde (4). A minor revision of 1 and new spectroscopic data for 1 and 2 are provided, along with associated anti-cancer activities of compounds.
MeSH terms
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Animals
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Antineoplastic Agents / chemistry*
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Antineoplastic Agents / isolation & purification
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Antineoplastic Agents / pharmacology
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CHO Cells
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Cell Line, Tumor
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Chlorophyta / chemistry*
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Cricetinae
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Diterpenes / chemistry*
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Diterpenes / isolation & purification
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Diterpenes / pharmacology
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Drug Screening Assays, Antitumor
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Euryarchaeota / chemistry
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Humans
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Indoles / chemistry
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Indoles / isolation & purification
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Indoles / pharmacology
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Magnetic Resonance Spectroscopy
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Molecular Conformation
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Plant Extracts / chemistry*
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Plant Extracts / isolation & purification
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Plant Extracts / pharmacology
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Solvents / chemistry
Substances
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4-hydroxydictyolactone
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8alpha,11-dihydroxypachydictyol A
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Antineoplastic Agents
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Diterpenes
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Indoles
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Plant Extracts
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Solvents
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dictyol E
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indole-3-carbaldehyde