Influence of a prolonged lateral position on induction of spinal anesthesia for cesarean delivery: a randomized controlled trial

Minerva Anestesiol. 2012 Jun;78(6):646-52. Epub 2012 Mar 13.

Abstract

Background: Maternal hypotension occurs commonly during cesarean delivery under spinal anesthesia. We evaluated whether hypotension due to aortocaval compression could be prevented by maintaining a lateral position after an intrathecal injection.

Methods: Eighty-six women undergoing elective cesarean delivery were enrolled. Spinal anesthesia was conducted in the right lateral position using 8 mg of hyperbaric bupivacaine and 15 µg of fentanyl. Patients were randomly assigned to maintain the right lateral position for 6 min before assuming the wedged supine position (group L), or to assume the wedged supine position immediately after the spinal injection (group S). Hypotension was defined as a decrease in mean arterial pressure to <80% of baseline. Ephedrine was given if blood pressure decreased to <70% of baseline. The incidence of hypotension and nausea, ephedrine requirement, maximal block height, and neonatal outcomes were evaluated.

Results: No significant between-group differences were observed in the lowest blood pressure, total ephedrine dose, or incidence of hypotension or nausea. Onset of hypotension was delayed (6 ± 2 vs. 10 ± 3 min, P<0.001), and the sensory block level was more cephalad in group L than in group S (T2 [C8-T5] vs. T4 [T1-T6], P=0.001). Apgar scores did not differ between the groups.

Conclusion: During spinal anesthesia for elective cesarean delivery, maintaining the lateral position for 6 min after an intrathecal injection of hyperbaric bupivacaine resulted in a more gradual and higher cephalad sensory block, without an increase in the incidence of maternal hypotension.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Anesthesia, Spinal / methods*
  • Cesarean Section*
  • Female
  • Humans
  • Hypotension / prevention & control*
  • Intraoperative Complications / prevention & control*
  • Patient Positioning*
  • Pregnancy
  • Prospective Studies
  • Single-Blind Method
  • Time Factors