Herein, we report a case of progressive coronary vasospasm in a 70-year-old man who had a long-standing history of metastatic gastrointestinal carcinoid tumor. Despite octreotide, nitrate, and calcium channel-blocker therapy, the patient's urinary 5-hydroxy-indole acetic acid level increased, coinciding with an increased frequency of flushing episodes with chest discomfort. In the cardiac catheterization laboratory, we captured an episode that was associated with diffuse right coronary artery spasm, ST-segment elevation, and intense symptoms. We attribute the patient's coronary vasospasm to his metastatic carcinoid disease.
Keywords: Angina pectoris, variant/drug therapy; coronary disease/physiopathology; coronary vasospasm/diagnosis/etiology/physiopathology; flushing/etiology; malignant carcinoid syndrome/complications; octreotide/administration & dosage; treatment outcome.