Unusual presentation of metastatic Ewing sarcoma to the ovary in a 13 year-old: a case report and review

Fetal Pediatr Pathol. 2012 Jun;31(3):159-63. doi: 10.3109/15513815.2012.659379. Epub 2012 Mar 13.

Abstract

Ewing sarcoma (ES) is the second most common bone malignancy in children and adolescents. Together with primitive neuroectodermal tumors (PNET), ES comprises the PNET/ES family. Metastasis is present in about 25% of patients at diagnosis and is most commonly found in the lung and bones. Primary PNET/ES of the ovary has been reported in many adult cases; however, secondary occurrences are rare. Here we present the clinical course of a 13-year-old patient with metastatic ES to the ovary without involvement of any other sites. To our knowledge, this is the second reported pediatric case of metastatic ES to the ovary.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Bone Neoplasms / pathology*
  • Bone Neoplasms / therapy
  • Combined Modality Therapy
  • Fatal Outcome
  • Female
  • Humans
  • Orthopedic Procedures
  • Ovarian Neoplasms / secondary*
  • Ovarian Neoplasms / therapy
  • Ovariectomy
  • Salpingectomy
  • Sarcoma, Ewing / secondary*
  • Sarcoma, Ewing / therapy