AIDS/HIV. HIV interplay with SAMHD1

Science. 2012 Mar 16;335(6074):1313-4. doi: 10.1126/science.1221057.
No abstract available

MeSH terms

  • Adaptive Immunity
  • Animals
  • Autoimmune Diseases of the Nervous System / genetics
  • DNA, Complementary / metabolism
  • Genes, Viral
  • HIV Infections / immunology
  • HIV Infections / virology*
  • HIV-1 / immunology*
  • HIV-1 / pathogenicity
  • HIV-1 / physiology*
  • HIV-2 / pathogenicity
  • Humans
  • Immunity, Innate
  • Monomeric GTP-Binding Proteins / chemistry
  • Monomeric GTP-Binding Proteins / genetics
  • Monomeric GTP-Binding Proteins / metabolism*
  • Mutation
  • Myeloid Cells / virology*
  • Nervous System Malformations / genetics
  • Nucleotides / metabolism
  • SAM Domain and HD Domain-Containing Protein 1
  • Simian Immunodeficiency Virus / pathogenicity
  • Viral Regulatory and Accessory Proteins / genetics
  • Viral Regulatory and Accessory Proteins / metabolism
  • Virus Replication

Substances

  • DNA, Complementary
  • Nucleotides
  • VPX protein, Human immunodeficiency virus 2
  • Viral Regulatory and Accessory Proteins
  • SAM Domain and HD Domain-Containing Protein 1
  • SAMHD1 protein, human
  • Monomeric GTP-Binding Proteins

Supplementary concepts

  • Aicardi-Goutieres syndrome