Two new antimicrobial flavanes from dragon's blood of Dracaena cambodiana

J Asian Nat Prod Res. 2012;14(5):436-40. doi: 10.1080/10286020.2012.668534. Epub 2012 Mar 22.

Abstract

Two new flavonoids, named cambodianins D (1) and E (2), together with two known flavanes (2S)-7,4'-dihydroxy-6,8-dimethylflavane (3) and (2S)-7,3'-dihydroxy-4'-methoxy-8-methylflavane (4), were isolated from dragon's blood of Dracaena cambodiana. The new compounds were determined by HR-ESI-MS and spectroscopic techniques (UV, IR, 1D, and 2D NMR). Compounds 1-3 exhibited antimicrobial activities.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Infective Agents / chemistry
  • Anti-Infective Agents / isolation & purification*
  • Anti-Infective Agents / pharmacology*
  • Dracaena / chemistry*
  • Drug Resistance, Bacterial / drug effects
  • Drugs, Chinese Herbal / chemistry
  • Drugs, Chinese Herbal / isolation & purification*
  • Drugs, Chinese Herbal / pharmacology*
  • Flavonoids / chemistry
  • Flavonoids / isolation & purification*
  • Flavonoids / pharmacology*
  • Methicillin-Resistant Staphylococcus aureus / drug effects
  • Microbial Sensitivity Tests
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Plant Extracts / chemistry*
  • Staphylococcus aureus / drug effects

Substances

  • Anti-Infective Agents
  • Drugs, Chinese Herbal
  • Flavonoids
  • Plant Extracts
  • cambodianin D
  • cambodianin E
  • dragon's blood