Intracranial extramedullary hematopoiesis in beta-thalassemia

Korean J Radiol. 2012 Mar-Apr;13(2):240-3. doi: 10.3348/kjr.2012.13.2.240. Epub 2012 Mar 7.

Abstract

Extramedullary hematopoiesis (EMH) represents tumor-like proliferation of hemopoietic tissue which complicates chronic hemoglobinopathy. Intracranial EMH is an extremely rare occurrence. Magnetic resonance imaging (MRI) offers a precise diagnosis. It is essential to distinguish EMH from other extradural central nervous system tumors, because treatment and prognosis are totally different. Herein, we report the imaging findings of beta-thalassemia in a 13-year-old boy complaining of weakness of left side of the body and gait disturbance; CT and MRI revealed an extradural mass in the right temporoparietal region.

Keywords: Beta-thalassemia; Computed tomography; Diffusion weighted imaging; Extramedullary hematopoiesis; Magnetic resonance imaging.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Brain Diseases / diagnosis
  • Brain Diseases / etiology*
  • Brain Diseases / surgery
  • Diagnosis, Differential
  • Hematopoiesis, Extramedullary*
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Tomography, X-Ray Computed
  • beta-Thalassemia / complications*