Hypogonadism secondary to hyperprolactinaemia: successful treatment but adverse consequences

Exp Clin Endocrinol Diabetes. 2012 May;120(5):311-3. doi: 10.1055/s-0031-1297994. Epub 2012 Mar 22.

Abstract

It is accepted that care must be taken in initiating testosterone replacement in hypogonadal individuals with historically low androgen levels. However less is reported about the influence of restoration of normal endogenous testosterone production on behaviour.Here we report how the adverse sequelae of successful treatment of hypogonadism secondary to hyperprolactinaemia, manifesting as irritability and low threshold to aggression, were managed through a joint approach between psychiatrist and physician.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aminoquinolines / adverse effects
  • Aminoquinolines / therapeutic use*
  • Behavior Therapy / methods
  • Dopamine Agonists / adverse effects
  • Dopamine Agonists / therapeutic use*
  • Humans
  • Hyperprolactinemia / drug therapy
  • Hyperprolactinemia / pathology*
  • Hypogonadism / blood*
  • Hypogonadism / drug therapy
  • Male
  • Pituitary Neoplasms / blood
  • Pituitary Neoplasms / drug therapy
  • Pituitary Neoplasms / pathology*

Substances

  • Aminoquinolines
  • Dopamine Agonists
  • quinagolide