Epidermal cell differentiation in cotton mediated by the homeodomain leucine zipper gene, GhHD-1

Plant J. 2012 Aug;71(3):464-78. doi: 10.1111/j.1365-313X.2012.05003.x. Epub 2012 May 28.

Abstract

Gossypium hirsutum L. (cotton) fibres are specialized trichomes a few centimetres in length that grow from the seed coat. Few genes directly involved in the differentiation of these epidermal cells have been identified. These include GhMYB25-like and GhMYB25, two related MYB transcription factors that regulate fibre cell initiation and expansion. We have also identified a putative homeodomain leucine zipper (HD-ZIP) transcription factor, GhHD-1, expressed in trichomes and early fibres that might play a role in cotton fibre initiation. Here, we characterize GhHD-1 homoeologues from tetraploid G. hirsutum and show, using reporter constructs and quantitative real-time PCR (qRT-PCR), that they are expressed predominantly in epidermal tissues during early fibre development, and in other tissues bearing epidermal trichomes. Silencing of GhHD-1 reduced trichome formation and delayed the timing of fibre initiation. Constitutive overexpression of GhHD-1 increased the number of fibres initiating on the seed, but did not affect leaf trichomes. Expression of GhHD-1 in cotton silenced for different fibre MYBs suggest that in ovules it acts downstream of GhMYB25-like, but is unaffected in GhMYB25- or GhMYB109-silenced plants. Microarray analysis of silencing and overexpression lines of GhHD-1 indicated that it potentially regulates the levels of ethylene and reactive oxidation species (ROS) through a WRKY transcription factor and calcium-signalling pathway genes to activate downstream genes necessary for cell expansion and elongation.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Calcium Signaling / physiology
  • Cell Differentiation / genetics*
  • Cell Differentiation / physiology
  • Cell Enlargement
  • Cotton Fiber
  • Ethylenes / metabolism
  • Gene Expression Regulation, Developmental / genetics*
  • Gene Expression Regulation, Plant / genetics
  • Genes, Homeobox
  • Gossypium / cytology
  • Gossypium / genetics
  • Gossypium / growth & development
  • Gossypium / physiology*
  • Leucine Zippers / genetics
  • Molecular Sequence Data
  • Phylogeny
  • Plant Components, Aerial / cytology
  • Plant Components, Aerial / genetics
  • Plant Components, Aerial / growth & development
  • Plant Components, Aerial / physiology
  • Plant Epidermis / cytology
  • Plant Epidermis / genetics
  • Plant Epidermis / growth & development
  • Plant Epidermis / physiology*
  • Plant Proteins / genetics
  • Plant Proteins / metabolism*
  • Plants, Genetically Modified
  • Promoter Regions, Genetic / genetics
  • Reactive Oxygen Species / metabolism
  • Seeds / cytology
  • Seeds / genetics
  • Seeds / growth & development
  • Seeds / physiology
  • Sequence Alignment
  • Time Factors
  • Transcription Factors / genetics
  • Transcription Factors / metabolism

Substances

  • Ethylenes
  • Plant Proteins
  • Reactive Oxygen Species
  • Transcription Factors
  • ethylene