Circulating soluble tumor necrosis factor related apoptosis inducing-ligand (TRAIL) is decreased in type-2 newly diagnosed, non-drug using diabetic patients

A Bisgin; A D Yalcin; R M Gorczynski

doi:10.1016/j.diabres.2012.02.028

Circulating soluble tumor necrosis factor related apoptosis inducing-ligand (TRAIL) is decreased in type-2 newly diagnosed, non-drug using diabetic patients

Diabetes Res Clin Pract. 2012 Jun;96(3):e84-6. doi: 10.1016/j.diabres.2012.02.028. Epub 2012 Mar 23.

Authors

A Bisgin¹, A D Yalcin, R M Gorczynski

Affiliation

¹ Department of Medical Genetics, Human Gene and Cell Therapy Center of Akdeniz University Hospital and Clinics, Antalya, Turkey. [email protected]

PMID: 22446096
DOI: 10.1016/j.diabres.2012.02.028

Abstract

We examined the association between serum sTRAIL measured by ELISA and HbA1C levels, pre/post-prandial blood glucose levels and body mass index in 22 newly diagnosed type-2 diabetic patients. A significant difference in sTRAIL levels was found between study group and controls.

MeSH terms

Adult
Aged
Apoptosis
Biomarkers / blood
Blood Glucose / metabolism*
Diabetes Mellitus, Type 2 / blood*
Enzyme-Linked Immunosorbent Assay
Fasting / blood
Female
Glycated Hemoglobin / metabolism*
Humans
Male
Middle Aged
Postprandial Period
TNF-Related Apoptosis-Inducing Ligand / blood*

Substances

Biomarkers
Blood Glucose
Glycated Hemoglobin A
TNF-Related Apoptosis-Inducing Ligand
hemoglobin A1c protein, human